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Observe Intently (1)lenacapavir will boost the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism.enzalutamide will minimize the level or effect of fentanyl by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Observe Intently. Coadministration of fentanyl with CYP3A4 inducers may lead into a re